4 Gauge vs PEScience Prolific Pre Workout [Only One Works!]

4 Gauge vs PEScience Prolific Pre Workout

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4 Gauge vs PEScience Prolific Pre Workout

Today we get the chance to compare two big products in our 4 Gauge vs PEScience Prolific Pre Workout review.

Which one is going to give us everything we need? Only one can win so which is the most impressive? A good start will be a product that can give us the following:

  • Increased energy
  • Enhanced focus
  • Greater muscle pumps
  • Big gains!

Anything less and they are in trouble. We’re going to be putting them both to the sword. It all begins with the companies themselves.

4 Gauge vs PEScience Prolific Pre Workout: Who Makes These Products?

Roar Ambition4 Gauge Pre Workout Supplement

Here we have the UK based company behind 4 Gauge.

They make everything to the approval of the FDA and GMP and review and amend their ingredients and dosages regularly. This ensures the user is getting the best possible version at all times.

With a generous money back guarantee and shipping directly from the UK and USA they have some impressive customer service values. If endorsements are your thing, then Roar Ambition have some great ones.

UFC fighter Diego Sanchez puts his name to their fat burner, Instant Knockout. They also have former Mr. Universe Robby Robinson promoting their T booster.

They only use natural ingredients, impressive stuff so far.

PESciencePEScience Prolific Pre Workout

Now we have the Florida based company that makes our second product today.

They seem to be big on quality control, dedicating a lot of space in this area. They talk about their slow approach to launching products as well, releasing just 7 in their first 4 years.

PEScience have a wider range now and these include BCAA drinks as well as Joint Support formulas. They promise no tingles (hopefully no Beta-Alanine then!) with this product as well as explosive energy and ultra-powerful pumps.

They advise taking one scoop, to begin with, building up to 2 maybe. This is because of the Caffeine content and is common for pre-workouts.

They have gone down the Amazon route of selling and seem to do well out of it. This doesn’t always mean a good product though, we have seen a lot of rubbish on there!

Time to see if this is an exception or not.

4 Gauge vs PEScience Prolific Pre Workout Ingredients

Now we can see which of these products is going to impress the most.

The early signs for both are good. They stay clear of proprietary blends. This means all the dosages are revealed and we can see how good each ingredient is.

Mutual Ingredients


Both products have got off to a fine start here.

For a pre-workout, this is as close to a vital ingredient as you can get. It is good for increasing blood flow. It turns into nitric oxide in the kidneys which then widens the blood vessels. This is what promotes blood flow and helps with the huge gains and muscle pumps everyone wants.

A common source is watermelons and it actually converts into Arginine in the body. This helps with Creatine synthesis. Since PEScience Prolific Pre Workout does not include Creatine, this is even more useful for them.

Their dosage of 6 g per 2 scoops is a very good and optimal amount. According to Examine.com, anything between 6 – 8 g is optimal. 4 Gauge has also included 6 g making them both very effective.

Caffeine Anhydrous

We could just call this Mr or Mrs. Versatile really.

It has so many uses that it can be found in almost every type of supplement. Nootropic benefit from its added focus and alertness. Fat burners benefit from the metabolism boost.

For a pre-workout, the energy increase is a great place to start. It will help you to get more out of every session and get you pumped as you walked through the gym door.

The anhydrous element of this ingredient just means it is a powdered form. This makes it easy to absorb by the body and because of this, it gets to work fast.

A safe dosage is vital with any stimulant. The problem is at 320 mg, they have given you an amount that leans to the high side. Anything over 200 mg can be too much for many people, especially in one go.

The 150 mg in 4 Gauge is a very sensible, yet effective amount. WebMD says that taking too much can cause nervousness, nausea, stomach irritation, insomnia, increased heart rate, and other side effects.


A great ingredient to include, especially when there is Caffeine around.

This is an ingredient that will help the body to cope with some of Caffeine’s negative effects.

L-Theanine is derived from Green Tea and is well known for helping the user to remain calm and in control when stimulants are present.

Examine.com says that it helps promote relaxation without drowsiness, making it synergistic with Caffeine.

Because the Caffeine content is quite high in PEScience Prolific Pre Workout, L-Theanine is an important ingredient. It isn’t going to stop the Caffeine from working but will help you to feel calm. Even though 4 Gauge have gone for a sensible dosage of Caffeine, this is still a good amount.

The 200 mg in both products means you are getting a good dosage.

Rhodiola Rosea

A good ingredient that we don’t always see enough of.

It is a Scandinavian herb and is known to raise spirits. By adding focus in the user it can help to work against the many distractions in the gym.

Examine.com says that it is popular for its adaptogenic properties (reducing fatigue and exhaustion in prolonged stressful situations).

The 100 mg from both is a good amount.

Individual Ingredients

4 Gauge

Creatine Monohydrate

A very good start to their individual ingredients.

Examine.com says that Creatine is often used by athletes to increase power output and lean mass.

What is really good is that it the backing of many studies and is a safe and effective ingredient. Creatine has also been found to aid physical and muscular performance. It is also a very effective recovery aid.

This is why it is also a good ingredient post workout. There is no bad time to get the recovery process going.

The reason for this is that Creatine can benefit the body at any time. One study shows us that supplementing Creatine during arm flexor strength training was found to lead to greater increases in arm flexor muscle strength, upper arm muscle area, and fat-free mass than strength training alone.

The 1 g in 4 Gauge is an effective amount that will really benefit the user.

Acetyl L-Carnitine

Another very good inclusion.

Anything that can aid fat burning as well as promote energy levels is going to be useful. With more energy, you can really get more out of your session.

WebMD backs this up and says Acetyl L-Carnitine helps the body to produce energy. They also say that it is important for heart and brain function, muscle movement, and many other body processes.

The 500 mg is a good amount.

Red Beet

The enhanced blood flow here is going to be of most use.

Because it raises plasma nitrate levels, your workout will be even better. The increased stamina means you can get even more from every session. Red Beet has been shown to be a natural and safe option.

The big muscle pumps need more blood flow and this is the ingredient to get that.

At 300 mg, it is another effective dosage.

Coconut Water Powder

The final ingredient in 4 Gauge and one that shows a great understanding of what you need from a complete pre-workout.

Because this product contains lots of ingredients that will help you to burn through a lot of energy and get through the bigger weights, you need to make sure you are hydrated properly.

Coconut Water Powder is useful for this. When your body is depleted of what it needs, this puts you at greater risk of injury. Coconut Water Powder will keep your body topped up with electrolytes and maintain fluid levels at a healthy level.

The 300 mg is definitely a sensible inclusion.

PEScience Prolific Pre Workout

Betaine Anhydrous

Derived from beets it is often thought to be good for muscles and workouts.

Betaine Anhydrous increases protein synthesis which has links to promoting muscle growth and strength. There are also studies that link it to producing Creatine.

This would help with muscle output, especially as this product doesn’t include Creatine. Still, there are more effective ingredients for this.

WebMD say that it helps in the metabolism of a chemical called homocysteine. They continue to add that this is involved in the normal function of many different parts of the body, including, blood, bones, eyes, heart, muscles and more.

The issue though is when they tell us more. They say that there is insufficient evidence to support its use as an exercise performance enhancer. However, they also comment there is some evidence to support strength in men who train though so it seems there is some conflict over its uses.

The 2.5 g appears to be high enough to have an effect.


A good ingredient, especially given the Caffeine content here.

Still, there are those who mistakenly think this is a stimulant. This is understandable to an extent. It is often included in energy drinks. In reality, though, the opposite is true. Taurine works to help the consumer deal with levels of stimulants in their body.

Taurine helps the user to stay in control. It is believed to work as an antioxidant and increases blood flow, therefore enhancing gym performance. The lack of human trials though is a bit of a concern. It has shown promise in animal studies but these aren’t what we are after.

Still, studies do show that Taurine can help to reduce soreness post workout which lessens the risk of injury. One study actually found that Taurine might be able to improve exercise performance for cardio.

The dosage of 1.5 g is around the amount used in the studies we have seen.


An ingredient better suited to a nootropic, but can still benefit a pre-workout.

Sure, a pre-workout should be targeting gains, even still, it can aid your concentration and brain capabilities.

Citicoline is certainly useful for boosting concentration and focus. It will even help you to remember information as well.

It gives added acetylcholine. This neurotransmitter increases your ability to learn as well as increases attention.

What you are actually getting in this product is a branded version called Cognizin. This has been proven by studies to increase brain energy by 13.6%.

Examine.com even refers to a study that found women who took Citicoline showed improved attentional focus and inhibition.

The 250 mg is a good amount.

Coffee Fruit Extract

Sometimes known as Coffee Berries, this ingredient is here to increase alertness.

We already have more than enough nutrients for this so we have a pointless inclusion really. Green Coffee Bean is basically Coffee before the color has been roasted out.

A popular ingredient in fat burners because of the chlorogenic acid, but as with a few of the ingredients in this product, isn’t what we are after.

4 Gauge vs PEScience Prolific Pre Workout Side Effects

The good news is that 4 Gauge contains natural ingredients at safe, yet effective dosages. There isn’t anything in there that concerns us.

This is pretty much the same for PEScience Prolific Pre Workout with the exception of the Caffeine content.

The 320 mg is on the high side if you want to double scoop and could result in jitters, nausea, headache, insomnia and more.

4 Gauge vs PEScience Prolific Pre Workout Pros and Cons

4 Gauge Pros

  • 100% natural ingredients
  • Increased energy levels
  • Enhanced performance when in the gym
  • No side effects
  • Zero artificial sweeteners
  • Low in calories
  • Great taste
  • Made in the USA
  • No energy crash

PEScience Prolific Pre Workout Pros

  • Some useful ingredients
  • Citrulline dosed well
  • Some useful cognitive boosters

4 Gauge Cons

  • No choice when it comes to flavors
  • Only available from the manufacturer

PEScience Prolific Pre Workout Cons

  • Ineffective ingredients
  • Caffeine content quite high

4 Gauge vs PEScience Prolific Pre Workout

Winner: 4 Gauge

4 Gauge Review - best pre-workout - get 1 free bottle

Read our full 4 Gauge Review

Buy 4 Gauge from www.4gauge.com

(Clean Lean Machine Tip: Buy 3 bottles and get a 4th bottle FREE whilst the offer is still available!)

This wasn’t as close as we had hoped in the end.

Both products have a lot of good going for them, but it was only 4 Gauge that provided a product without any filler and with sensible stimulant levels.

Their inclusion of Creatine, Acetyl L-Carnitine and Coconut Water Powder was a big plus point for them as well.

4 Gauge is a clever product that goes beyond the gains, it helps with hydration and focus as well. There aren’t many companies that go as far when trying to make a useful supplement.

A great all-around pre-workout that uses proven ingredients at optimal dosages, it is the product that many people have been looking for.

Buy 4 Gauge from www.4gauge.com

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